Reference : LIS1 and spindle orientation in neuroepithelial cells.
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/10993/2742
LIS1 and spindle orientation in neuroepithelial cells.
English
Schwamborn, Jens Christian mailto [University of Luxembourg > Faculty of Science, Technology and Communication (FSTC) > Life Science Research Unit >]
Knoblich, Juergen A. [> >]
2008
Cell Stem Cell
2
3
193-4
Yes (verified by ORBilu)
International
1875-9777
United States
[en] 1-Alkyl-2-acetylglycerophosphocholine Esterase/metabolism ; Animals ; Brain/embryology ; Cell Division/physiology ; Mice ; Microtubule-Associated Proteins/metabolism ; Mitotic Spindle Apparatus/physiology ; Neuroepithelial Cells/cytology/physiology ; Stem Cells/cytology/physiology
[en] Asymmetric stem cell division is thought to require precise orientation of the mitotic spindle. However, a recent study in Cell (Yingling et al., 2008) analyzes the role of LIS1 in the developing mouse brain and shows that spindle orientation is more important during early, symmetric progenitor cell divisions than for later asymmetric divisions.
http://hdl.handle.net/10993/2742

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