Reference : Etude de differentes methodes pour la mise en evidence des autoanticorps anti-glutama...
Scientific journals : Article
Human health sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/27225
Etude de differentes methodes pour la mise en evidence des autoanticorps anti-glutamate-decarboxylase associes au developpement du diabete insulinodependant
French
[en] A comparative study of assays used for the detection of glutamic acid decarboxylase autoantibodies and their relevance in the follow-up of insulin- dependent diabetes
Humbel, R. L. [Laboratoire d'Immunopathologie, Centre Hospitalier de Luxembourg, 4, rue Barblé, Ll210 Luxembourg, Luxembourg]
Guillaume, A. C. [Laboratoire d'Immunopathologie, Centre Hospitalier de Luxembourg, 4, rue Barblé, Ll210 Luxembourg, Luxembourg]
Schmit, P. [Laboratoire d'Immunopathologie, Centre Hospitalier de Luxembourg, 4, rue Barblé, Ll210 Luxembourg, Luxembourg]
Gilson, G. [Laboratoire d'Immunopathologie, Centre Hospitalier de Luxembourg, 4, rue Barblé, Ll210 Luxembourg, Luxembourg]
De Beaufort, Carine mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Michel, G. [Epidip-CRP-Study Group, Centre Hospitalier de Luxembourg, 4, rue Barblé, Ll210 Luxembourg, Luxembourg]
Mauch, L. [Elias Entwicklungslabor, Elias, Freiburg, Germany]
1997
Immuno-Analyse et Biologie Specialisee
12
5
275-279
Yes
09232532
[en] Autoantibodies ; ELISA ; GAD ; Glutamate- decarboxylase ; Insulin dependent diabetes ; RIA
[en] Autoantibodies to glutamate-decarboxylase (GAD) are present in the serum of patients with insulin dependent diabetes (DID) even before the development of the overt diabetes. These antibodies react predominantly with the native GAD. Various methods have been studied (radio immunoassay [RIA] and enzyme- linked immunosorbent assay [ELISA]). It was observed that at the present time only RIA-tests, in which GAD is presented in fluid phase, are able to detect antibodies.
http://hdl.handle.net/10993/27225

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