Reference : A decade of metaproteomics: where we stand and what the future holds
Scientific journals : Article
Life sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/26859
A decade of metaproteomics: where we stand and what the future holds
English
Wilmes, Paul mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Heintz-Buschart, Anna mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Bond, Philip [University of Queensland > Advanced Water Management Centre]
2015
Proteomics
Wiley-VCH Verlag Gmbh
Yes (verified by ORBilu)
1615-9853
1615-9861
Weinheim
Germany
[en] Integrated omics ; Metagenomics ; Metaproteomics ; Microbial community ; Microbial systems ecology
[en] We are living through exciting times during which we are able to unravel the “microbial dark matter” in and around us through the application of high-resolution “meta-omics”. Metaproteomics offers the ability to resolve the major catalytic units of microbial populations and thereby allows the establishment of genotype-phenotype linkages from in situ samples. A decade has passed since the term “metaproteomics” was first coined and corresponding analyses were carried out on mixed microbial communities. Metaproteomics has yielded many important insights into microbial ecosystem function in the various environmental settings where it has been applied. Although initial progress in analytical capacities and resulting numbers of proteins identified was extremely fast, this trend slowed rapidly. Here we highlight several representative metaproteomic investigations of activated sludge, acid mine drainage biofilms, freshwater and seawater microbial communities, soil, and human gut microbiota. By using these case studies, we highlight current challenges and possible solutions for metaproteomics to realize its full potential, i.e. to enable conclusive links between microbial community composition, physiology, function, interactions, ecology, and evolution.
Luxembourg Centre for Systems Biomedicine (LCSB): Eco-Systems Biology (Wilmes Group)
http://hdl.handle.net/10993/26859
10.1002/pmic.201500183

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
Wilmes_et_al-2015-PROTEOMICS.pdfAuthor postprint431.45 kBView/Open

Bookmark and Share SFX Query

All documents in ORBilu are protected by a user license.