Reference : Controlling complexity: the clinical relevance of mouse complex genetics.
Scientific journals : Article
Life sciences : Genetics & genetic processes
http://hdl.handle.net/10993/26639
Controlling complexity: the clinical relevance of mouse complex genetics.
English
Schughart, Klaus [> >]
Libert, Claude [> >]
Kas, Martien J. [> >]
Andreux, Penelope [> >]
Aransay, Ana Maria [> >]
Auwerx, Johan [> >]
Balling, Rudi mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) >]
Banerjee, Sreeparna [> >]
Bezerianos, Anastasios [> >]
Bragonzi, Alessandra Desj [> >]
Brockmann, Gudrun A. [> >]
Brown, Steve [> >]
Campbell-Tofte, Joan [> >]
Cendelin, Jan [> >]
Chatziioannou, Aristotelis [> >]
Chen, Duan [> >]
Crusio, Wim [> >]
Dimitrakopoulou, Konstantina [> >]
Falcon, Juan M. [> >]
Forejt, Jiri [> >]
Franken, Paul [> >]
Frohlich, Leopold F. [> >]
Herault, Yann [> >]
Hovatta, Iiris [> >]
Iraqi, Fuad A. [> >]
Jansen, Ritsert C. [> >]
Kaczmarek, Leszek [> >]
Kas, Martien [> >]
Knapska, Ewelina [> >]
Koks, Sulev [> >]
Kolisis, Fragiskos [> >]
Korostynski, Michal [> >]
Lammert, Frank [> >]
Lehrach, Hans [> >]
Lengeling, Andreas [> >]
Libert, Claude [> >]
Montagutelli, Xavier [> >]
Morahan, Grant [> >]
Mott, Richard [> >]
Panthier, Jean-Jacques [> >]
Przewlocki, Ryszard [> >]
Ranki, Annamari [> >]
Santos, Javier [> >]
Severcan, Feride [> >]
Schalkwyk, Leonard [> >]
Schughart, Klaus [> >]
Smit, August B. [> >]
Terasmaa, Anton [> >]
Vasar, Eero [> >]
Zatloukal, Kurt [> >]
2013
European journal of human genetics : EJHG
21
11
1191-6
Yes (verified by ORBilu)
1018-4813
1476-5438
England
[en] Animals ; Biomedical Research ; Humans ; Mice ; Models, Animal ; Reverse Genetics
[en] Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Luxembourg Centre for Systems Biomedicine (LCSB): Experimental Neurobiology (Balling Group)
http://hdl.handle.net/10993/26639
10.1038/ejhg.2013.79

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