Reference : Training an asymmetric signal perceptron through reinforcement in an artificial chemistry
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
Engineering, computing & technology : Computer science
Computational Sciences
Training an asymmetric signal perceptron through reinforcement in an artificial chemistry
Banda, Peter mailto [Portland State University > Department of Computer Science]
Teuscher, Christof [> >]
Stefanovic, Darko [> >]
Journal of The Royal Society Interface
The Royal Society
[en] chemical perceptron ; representation asymmetry ; reinforcement learning ; mass-action kinetics ; thresholding ; robustness
[en] State-of-the-art biochemical systems for medical applications and chemical computing are application-specific and cannot be reprogrammed or trained once fabricated. The implementation of adaptive biochemical systems that would offer flexibility through programmability and autonomous adaptation faces major challenges because of the large number of required chemical species as well as the timing-sensitive feedback loops required for learning. In this paper, we begin addressing these challenges with a novel chemical perceptron that can solve all 14 linearly separable logic functions. The system performs asymmetric chemical arithmetic, learns through reinforcement and supports both Michaelis–Menten as well as mass-action kinetics. To enable cascading of the chemical perceptrons, we introduce thresholds that amplify the outputs. The simplicity of our model makes an actual wet implementation, in particular by DNA-strand displacement, possible.

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