Reference : Susceptibility-Weighted MRI for Deep Brain Stimulation: Potentials in Trajectory Planning
Scientific journals : Article
Life sciences : Anatomy (cytology, histology, embryology...) & physiology
Engineering, computing & technology : Multidisciplinary, general & others
Human health sciences : Surgery
http://hdl.handle.net/10993/23613
Susceptibility-Weighted MRI for Deep Brain Stimulation: Potentials in Trajectory Planning
English
Hertel, Frank mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Husch, Andreas mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Dooms, Georges [Centre Hospitalier de Luxembourg > Neuroradiology]
Bernard, Florian mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Gemmar, Peter [Trier University of Applied Sciences > Computerscience]
2015
Stereotactic & Functional Neurosurgery
S. Karger
93
5
303-308
Yes (verified by ORBilu)
International
1011-6125
1423-0372
[en] deep brain stimulation ; susceptibility-weighted MRI
[en] Background: Deep brain stimulation (DBS) trajectory plan- ning is mostly based on standard 3-D T1-weighted gado- linium-enhanced MRI sequences (T1-Gd). Susceptibility- weighted MRI sequences (SWI) show neurovascular struc- tures without the use of contrast agents. The aim of this study was to investigate whether SWI might be useful in DBS trajectory planning. Methods: We performed bilateral DBS planning using conventional T1-Gd images of 10 patients with different kinds of movement disorders. Afterwards, we matched SWI sequences and compared the visibility of vas- cular structures in both imaging modalities. Results: By ana- lyzing 100 possible trajectories, we found a potential vascu- lar conflict in 13 trajectories based on T1-Gd in contrast to 53 in SWI. Remarkably, all vessels visible in T1-Gd were also de- picted in SWI, whereas SWI showed many additional vascular structures which could not be identified in T1-Gd. Conclu- sion/Discussion: The sensitivity for detecting neurovascular structures for DBS planning seems to be significantly higher
in SWI. As SWI does not require a contrast agent, we suggest that SWI may be a valuable alternative to T1-Gd MRI for DBS trajectory planning. Furthermore, the data analysis suggests that vascular interactions of DBS trajectories might be more frequent than expected from the very low incidence of symptomatic bleedings. The explanation for this is currently the subject of debate and merits further studies.
Luxembourg Centre for Systems Biomedicine (LCSB): Systems Control (Goncalves Group) ; Centre Hospitalier de Luxembourg: National Department of Neurosurgery (Hertel Group)
Fonds National de la Recherche - FnR
Researchers ; Professionals
http://hdl.handle.net/10993/23613
10.1159/000433445

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