Reference : Biexcitability and Bursting Mechanisms in Neural and Genetic Circuits
Scientific congresses, symposiums and conference proceedings : Paper published in a book
Life sciences : Multidisciplinary, general & others
http://hdl.handle.net/10993/20330
Biexcitability and Bursting Mechanisms in Neural and Genetic Circuits
English
Gifany, Peyman mailto []
Goncalves, Jorge mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
2014
The proceedings of the 19th World Congress The International Federation of Automatic Control
Yes
19th World Congress The International Federation of Automatic Control
August 24-29, 2014
Cape Town
South Africa
[en] This paper compares mechanisms for generating repetitive spikes (bursts) in neural and
transcriptional circuits. Neurons generate bursts followed by refractory periods controlled by ion
channels in the membrane. In contrast, in gene transcription the bursts occur during a short time period followed by silent periods regulated by sis-regulatory elements. The role of excitability in producing different patterns of bursts is discussed by comparing the topology of a neural model with natural and synthetic transcriptional genetic circuits. In particular, a special bi-excitable architecture which embeds two excitable states are compared in these systems.
http://hdl.handle.net/10993/20330

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