Reference : From developmental biology to developmental toxicology.
Scientific journals : Article
Scientific journals : Article
http://hdl.handle.net/10993/1543
From developmental biology to developmental toxicology.
English
Balling, Rudi mailto [University of Luxembourg > Luxembourg Centre for Systems Biomedicine (LCSB) > >]
Hrabe de Angelis, M. [> >]
2000
Annals of the New York Academy of Sciences
919
239-45
Yes (verified by ORBilu)
0077-8923
UNITED STATES
[en] Animals ; Developmental Biology/trends ; Drosophila ; Drug Resistance/genetics ; Ethylnitrosourea/pharmacology/toxicity ; Genetic Predisposition to Disease ; Genome, Human ; Genotype ; Humans ; Mice ; Mutagenesis/drug effects/genetics ; Mutagens/pharmacology/toxicity ; Phenotype ; Toxicology/trends ; Xenobiotics/pharmacology/toxicity
[en] Progress derived from the human genome project will have tremendous impact on toxicology. Questions concerning genetic susceptibility or resistance to toxic compound exposure and the dissection of the molecular mechanisms involved will be at the forefront of future toxicological research. In recent years, it was recognized that many of the molecular control mechanisms of embryogenesis have been conserved during evolution. The relevance of these observations for toxicology and the application of genetic approaches using mouse mutants as a tool for functional genome analysis are discussed.
http://hdl.handle.net/10993/1543

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