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See detail150 ans de chemins de fer luxembourgeois (1859-2009). De la fin d'un isolement au début d'une mobilité durable
Scuto, Denis UL

in 150 Joer Eisebunn zu Lëtzebuerg, 1859 - 2009 (2009)

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See detail16 GHz Bandwidth MSM Photodetector and 45/85 GHz fT/fmax HEMT Prepared on an Identical InGaAs/InP Layer Structure
Horstmann, M.; Schimpf, K.; Marso, Michel UL et al

in Electronics Letters (1996), 32

Detailed reference viewed: 63 (0 UL)
See detailA 16S rRNA gene Illumina–based barcoded assay design for high throughput characterisation of microbial communities from anaerobic digesters
Calusinska, Magdalena; Goux, Xavier; Muller, Emilie UL et al

Poster (2014)

High throughput sequencing of 16S/18S rRNA gene is becoming an indispensable tool to explore microbial community ecology. To date, most of the studies using next generation amplicon sequencing of ... [more ▼]

High throughput sequencing of 16S/18S rRNA gene is becoming an indispensable tool to explore microbial community ecology. To date, most of the studies using next generation amplicon sequencing of microorganisms involved in the anaerobic digestion process (AD) are based on the 454 pyrosequencing. However, the cost per read obtained with the Illumina technology is currently less than 1/100 of that for the 454 pyrosequencing, thus enabling throughout sequencing and larger number of samples to be analysed per study (e.g. given the current Miseq output, around 100 000 reads per sample can be expected for a pool of 96 libraries). Moreover, the Illumina technology is less biased by the GC content of the template and currently allows for a relatively long sequence read of 600 bp (2 x 300bp). This consideration is particularly important, since longer sequences permit for more accurate assignment to a taxonomic group. Here, we designed and optimized an Illumina–based 16S rRNA amplicon approach for a high throughput characterization of microbial communities from different AD. [less ▲]

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See detail17 The epidemiology and immunogenetics of IDDM in Italian-heritage populations. Diabetes Epidemiology Research International (DERI) Study Group
Colle, E.; Lounamaa, R.; Tuomilehto, J. et al

in Diabetes/Metabolism Reviews (1990), 6

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See detail17beta-estradiol prevents programmed cell death in cardiac myocytes.
Pelzer, T.; Neumann, M.; deJager, T. et al

in Biochemical and biophysical research communications (2000), 268(1), 192-200

The cardioprotective effects of estrogens are clearly established. However, the underlying mechanisms are poorly understood. Because programmed cell death (apoptosis) probably contributes to the loss of ... [more ▼]

The cardioprotective effects of estrogens are clearly established. However, the underlying mechanisms are poorly understood. Because programmed cell death (apoptosis) probably contributes to the loss of cardiac myocytes in heart failure and because estrogens prevent apoptosis in breast cancer cells, we investigated whether the loss of cardiac myocytes by programmed cell death could be prevented by physiological doses of 17beta-estradiol. Apoptosis of cultured cardiac myocytes was induced by staurosporine. 17beta-estradiol (10 nM) had an antiapoptotic effect as determined by morphological analysis, vital staining using the Hoechst dye 33342 and terminal transferase dUTP nick-end labeling (TUNEL). As a potential mechanism for the antiapoptotic effect of 17beta-estradiol we found a reduced activity of the ICE-like protease caspase-3 in hormone-treated myocytes. Furthermore, inhibition of apoptosis by estradiol was associated with a reduced activity of NF-kappaB transcription factors, particularly p65/RelA and p50. To our knowledge, these data provide the first indication that 17beta-estradiol in physiological concentrations inhibits apoptosis in cardiac myocytes. The antiapoptotic effect of estrogens might contribute to the known cardioprotective effect of estrogens and provides a starting point for the development of future treatment options. [less ▲]

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See detail18. IGEB-Konferenz in Luxemburg
Sagrillo, Damien UL

in Revue Musicale (2007)

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See detailDas 18. Jahrhundert: eine Beschleunigung
Lehners, Jean-Paul UL; Hausberger, Bernd

in Hausberger, Bernd; Lehners, Jean-Paul (Eds.) Die Welt im 18. Jahrhundert. (2011)

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See detail1839
Kmec, Sonja UL

in Kmec, Sonja; Margue, Michel; Péporté, Pit (Eds.) et al Lieux de mémoire au Luxembourg. Usages du passé et construction nationale / Erinnerungsorte in Luxemburg. Umgang mit der Vergangenheit und Konstruktion der Nation (2007)

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See detail1839 ou comment le Luxembourg s'est inventé son anniversaire
Scuto, Denis UL

Article for general public (2014)

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See detail1867, Napoléon III, Bismarck et un record
Scuto, Denis UL

in Tageblatt (2017)

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See detail19 GHz vertical Si p-channel MOSFET
Moers, J.; Klaes, D.; Tönnesmann, A. et al

in Electronics Letters (1999), 35(1999), 239-240

Vertical Si p-MOSFETs with channel lengths of 100nm were fabricated using selective low pressure chemical vapour deposition (LPCVD) epitaxial growth and conventional i-line lithography. The layout, called ... [more ▼]

Vertical Si p-MOSFETs with channel lengths of 100nm were fabricated using selective low pressure chemical vapour deposition (LPCVD) epitaxial growth and conventional i-line lithography. The layout, called VOXFET, reduces gate to source/drain overlap capacitances, thus improving high speed applications. Transistors with a gate width of 12 um and gate oxide thickness of 10nm show transconductances gM of 200mS/mm and measured cutoff frequencies of fT = 8.7GHz and fMAX = 19.2 GHz. [less ▲]

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See detailDas 19. Jahrhundert als Mediengesellschaft
Lenz, Thomas UL

in MEDIENwissenschaft: Rezensionen, Reviews (2010), (02), 195-197

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See detail1919: L'autre référendum
Scuto, Denis UL

Article for general public (2015)

Weekly column on contemporary history ("L'histoire du temps présent") in Luxembourg newspaper Tageblatt, here on the referendum of 1919 about monarchy or republic for Luxembourg

Detailed reference viewed: 36 (2 UL)
See detail1919: Quel avenir pour la monarchie?
Scuto, Denis UL

in Muller, Jean-Claude (Ed.) 100 Joer Lëtzebuerger Dynastie : collections et souvenirs de la Maison grand-ducale. Catalogue de l’exposition au Musée national d’histoire et d’art, (1990)

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See detail1933-1939. Die Musikseiten des Tageblatt
Sagrillo, Damien UL

Article for general public (2013)

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See detailThe 1968 Movement Revisited – Education and the Distinction in Values, Political Interest and Political Participation in West Germany
Hadjar, Andreas UL; Schlapbach, Florian

in German Politics (2009), 18(2), 180-200

The aim of this paper is to take a look at the 1968 generation in West Germany about 40 years after the 1968 events. Whether there was a 1968 generation in the narrow sense of the word will be explored ... [more ▼]

The aim of this paper is to take a look at the 1968 generation in West Germany about 40 years after the 1968 events. Whether there was a 1968 generation in the narrow sense of the word will be explored. While comparing the 1968 generation with earlier and later cohorts, political interest, political activity and (postmaterialist) values will be analysed. Education will be theorised as a main mechanism that distinguishes the 1968 generation from earlier generations. Quantitative analyses will be performed employing a temporal perspective and including age, period and cohort effects - so that socialisation as well as individual change over the life cycle and macro influences can be taken into account. The results show a strong influence of education on political interest, political activity and postmaterialism. Therefore, what is called the '1968 generation' only applies to the more highly educated people of this generation. [less ▲]

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See detail1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation.
Helming, Laura; Bose, Jens; Ehrchen, Jan et al

in Blood (2005), 106(13), 4351-8

1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism. In addition, 1alpha,25(OH)2D3 ... [more ▼]

1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism. In addition, 1alpha,25(OH)2D3 is known to mediate predominantly immunosuppressive responses in vitro and in vivo. It has been demonstrated that macrophages can produce 1alpha,25(OH)2D3 on activation with interferon gamma (IFN-gamma), although little is understood about the biologic significance of this response. We show here that 1alpha,25(OH)2D3 can selectively suppress key effector functions of IFN-gamma-activated macrophages. Among these are the suppression of listericidal activity, the inhibition of phagocyte oxidase-mediated oxidative burst, and the suppression of important IFN-gamma-induced genes, including Ccl5, Cxcl10, Cxcl9, Irf2, Fcgr1, Fcgr3, and Tlr2. The deactivation of IFN-gamma-stimulated macrophages is dependent on a functional vitamin D receptor and 1alpha,25(OH)2D3 acts specifically on IFN-gamma-activated macrophages, whereas the steroid has no effects on resting macrophages. Therefore, the 1alpha,25(OH)2D3-mediated suppression of macrophage functions is distinct from previously described macrophage deactivation mechanisms. In conclusion, our data indicate that the production of 1alpha,25(OH)2D3 by IFN-gamma-stimulated macrophages might be an important negative feedback mechanism to control innate and inflammatory responses of activated macrophages. [less ▲]

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