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See detailSecure Number Theoretic Transform and Speed Record for Ring-LWE Encryption on Embedded Processors
Seo, Hwajeong; Liu, Zhe UL; Park, Taehwan et al

in The 20th Annual International Conference on Information Security and Cryptology - ICISC2017 (2017, December 30)

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See detailRecording Belgium's Gravitational History
Van Camp, Michel; Francis, Olivier UL; Lecocq, Thomas

in EOS : Transactions, American Geophysical Union (2017)

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See detailGenetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.
McCormack, Mark; Gui, Hongsheng; Ingason, Andres et al

in Neurology (2017)

OBJECTIVE: To characterize, among European and Han Chinese populations, the genetic predictors of maculopapular exanthema (MPE), a cutaneous adverse drug reaction common to antiepileptic drugs. METHODS ... [more ▼]

OBJECTIVE: To characterize, among European and Han Chinese populations, the genetic predictors of maculopapular exanthema (MPE), a cutaneous adverse drug reaction common to antiepileptic drugs. METHODS: We conducted a case-control genome-wide association study of autosomal genotypes, including Class I and II human leukocyte antigen (HLA) alleles, in 323 cases and 1,321 drug-tolerant controls from epilepsy cohorts of northern European and Han Chinese descent. Results from each cohort were meta-analyzed. RESULTS: We report an association between a rare variant in the complement factor H-related 4 (CFHR4) gene and phenytoin-induced MPE in Europeans (p = 4.5 x 10(-11); odds ratio [95% confidence interval] 7 [3.2-16]). This variant is in complete linkage disequilibrium with a missense variant (N1050Y) in the complement factor H (CFH) gene. In addition, our results reinforce the association between HLA-A*31:01 and carbamazepine hypersensitivity. We did not identify significant genetic associations with MPE among Han Chinese patients. CONCLUSIONS: The identification of genetic predictors of MPE in CFHR4 and CFH, members of the complement factor H-related protein family, suggest a new link between regulation of the complement system alternative pathway and phenytoin-induced hypersensitivity in European-ancestral patients. [less ▲]

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See detailThermotropic Liquid Crystal-Assisted Chemical and Biological Sensors
Popov, Nicolai; Honaker, Lawrence William UL; Popova, Maia et al

in Materials (2017), 11(20),

In this review article, we analyze recent progress in the application of liquid crystal-assisted advanced functional materials for sensing biological and chemical analytes. Multiple research groups ... [more ▼]

In this review article, we analyze recent progress in the application of liquid crystal-assisted advanced functional materials for sensing biological and chemical analytes. Multiple research groups demonstrate substantial interest in liquid crystal (LC) sensing platforms, generating an increasing number of scientific articles. We review trends in implementing LC sensing techniques and identify common problems related to the stability and reliability of the sensing materials as well as to experimental set-ups. Finally, we suggest possible means of bridging scientific findings to viable and attractive LC sensor platforms. [less ▲]

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See detailDamnatio memoriae
Scuto, Denis UL

Article for general public (2017)

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See detailCalculating the Malliavin derivative of some stochastic mechanics problems
Hauseux, Paul UL; Hale, Jack UL; Bordas, Stéphane UL

in PLoS ONE (2017), 12(12), 0189994

The Malliavin calculus is an extension of the classical calculus of variations from deterministic functions to stochastic processes. In this paper we aim to show in a practical and didactic way how to ... [more ▼]

The Malliavin calculus is an extension of the classical calculus of variations from deterministic functions to stochastic processes. In this paper we aim to show in a practical and didactic way how to calculate the Malliavin derivative, the derivative of the expectation of a quantity of interest of a model with respect to its underlying stochastic parameters, for four problems found in mechanics. The non-intrusive approach uses the Malliavin Weight Sampling (MWS) method in conjunction with a standard Monte Carlo method. The models are expressed as ODEs or PDEs and discretised using the finite difference or finite element methods. Specifically, we consider stochastic extensions of; a 1D Kelvin-Voigt viscoelastic model discretised with finite differences, a 1D linear elastic bar, a hyperelastic bar undergoing buckling, and incompressible Navier-Stokes flow around a cylinder, all discretised with finite elements. A further contribution of this paper is an extension of the MWS method to the more difficult case of non-Gaussian random variables and the calculation of second-order derivatives. We provide open-source code for the numerical examples in this paper. [less ▲]

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See detailWWII, Russians in Luxembourg: Sowjetesch Zwangsaarbechter zu Lëtzebuerg
Molitor, Maurice; Ganschow, Inna UL

Speeches/Talks (2017)

Am Kader vun engem Recherche-Projet iwwer "100 Joer russesch Emigratioun op Lëtzebuerg" fuerscht d'Inna Ganschow, mat der Ënnerstëtzung vun der Lydie-Schmit-Stëftung, ënnert anerem och iwwer d'Lous vu ... [more ▼]

Am Kader vun engem Recherche-Projet iwwer "100 Joer russesch Emigratioun op Lëtzebuerg" fuerscht d'Inna Ganschow, mat der Ënnerstëtzung vun der Lydie-Schmit-Stëftung, ënnert anerem och iwwer d'Lous vu sowjeteschen Zwangsaarbechter, déi an de Joren 1942 bis 44 op Lëtzebuerger Schmelzen an a Lëtzebuerger Bauerebetriber geschafft hunn. [less ▲]

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See detailWorkshop on Supergeometry and Applications
Bruce, Andrew UL; Poncin, Norbert UL

Report (2017)

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See detailCoupled CFD-DEM with Heat and Mass transfer to Investigate the Melting of a Granular Packed Bed
Baniasadi, Mehdi UL; Baniasadi, Maryam UL; Peters, Bernhard UL

in Chemical Engineering Science (2017)

The eXtended Discrete Element Method (XDEM) platform which is a Coupled Eulerian-Lagrangian framework with heat and mass transfer, is extended for melting of granular packed beds. In this method, the ... [more ▼]

The eXtended Discrete Element Method (XDEM) platform which is a Coupled Eulerian-Lagrangian framework with heat and mass transfer, is extended for melting of granular packed beds. In this method, the fluid is simulated by computational fluid dynamics (CFD) and the soft-sphere discrete element approach (DEM) is used for the particle system. A four-way coupling accounts for solid-liquid interaction via drag and buoyancy forces and the collisions between the particles and the walls. The contact forces between the particles and wall-particle contacts have been calculated by the hertz-mindlin model. The particles heat up, melt and shrink due to heat and mass exchange, and the temperature distributions inside the particles are described. In order to validate the method, melting of a single ice particle and of a packed bed of ice in flowing water have been carried out. Very good agreement between the simulation and experiment has been achieved. The effects of the temperature and velocity of flowing water on melting rate are also discussed. [less ▲]

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See detailAn elementary proof of the formal rigidity of the Witt and Virasoro algebra
Schlichenmaier, Martin UL

Scientific Conference (2017, December 19)

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See detailHomotopical Geometry over Differential Operators and Batalin-Vilkovisky Complex
Poncin, Norbert UL

Presentation (2017, December 18)

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See detailThe Missing Risk Premium in Exchange Rates
Penasse, Julien UL

Scientific Conference (2017, December 15)

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See detailTemPsy-Check: a Tool for Model-driven Trace Checking of Pattern-based Temporal Properties
Dou, Wei UL; Bianculli, Domenico UL; Briand, Lionel UL

in Proceedings of RV-CUBES 2017: an International Workshop on Competitions, Usability, Benchmarks, Evaluation, and Standardisation for Runtime Verification Tools (2017, December 14)

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See detailHigher Supergeometry Revisited
Poncin, Norbert UL

Presentation (2017, December 14)

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See detailOn the Risk of Tool Over-tuning in Runtime Verification Competitions
Bianculli, Domenico UL; Krstic, Srdan

in Proceedings of RV-CUBES 2017: an International Workshop on Competitions, Usability, Benchmarks, Evaluation, and Standardisation for Runtime Verification Tools (2017, December 14)

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See detailModelling argumentation on Axiom of Choice in ASPIC-END -- Technical report
Cramer, Marcos UL

Report (2017)

In this technical report, we present an application of the structured argumentation methodology to a debate in the foundations of mathematics. We work with ASPIC-END, a recently proposed adaptation of the ... [more ▼]

In this technical report, we present an application of the structured argumentation methodology to a debate in the foundations of mathematics. We work with ASPIC-END, a recently proposed adaptation of the structured argumentation framework ASPIC+ which can incorporate debates about logical principles, natural deduction style arguments and explanations. We apply this framework to build a preliminary formal model of parts of the debate that mathematicians had about the Axiom of Choice in the early 20th century. Furthermore, we briefly discuss the insight into the strengths and drawbacks of the modeling capacities of ASPIC-END that we have gained from producing this model. [less ▲]

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See detailMilitary Migrants. Luxembourgers in the Colonial Army of the Dutch East Indies
Bosma, Ulbe; Kolnberger, Thomas UL

in Itinerario (2017), 41(3), 555-580

Among the roughly 150,000 soldiers sent to the Dutch East Indies between 1815 and 1914, the Luxembourg contingent made up a tiny minority of just 1,075 men. Based upon extensive research into their ... [more ▼]

Among the roughly 150,000 soldiers sent to the Dutch East Indies between 1815 and 1914, the Luxembourg contingent made up a tiny minority of just 1,075 men. Based upon extensive research into their careers, data on these soldiers provide further clues to understanding what drove Europe’s young men to become colonial soldiers. The results of this national case study will be compared with earlier investigations by Bossenbroek and Bosma on recruits for the Dutch colonial army. Similar to the Dutch soldiers, their Luxembourg counterparts had a predominantly urban provenance. However, in contrast to the Dutch, they did not have a strong military background, and it appears that fewer Luxembourgers stayed behind in the Dutch East Indies after their tour of duty. They were more attracted by the payments that the recruiters doled out in advance, particularly at a time of economic crisis, than in a career in the tropics. [less ▲]

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See detailResolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.
Lucarelli, Philippe UL; Schilling, Marcel; Kreutz, Clemens et al

in Cell Systems (2017)

Upon stimulation of cells with transforming growth factor beta (TGF-beta), Smad proteins form trimeric complexes and activate a broad spectrum of target genes. It remains unresolved which of the possible ... [more ▼]

Upon stimulation of cells with transforming growth factor beta (TGF-beta), Smad proteins form trimeric complexes and activate a broad spectrum of target genes. It remains unresolved which of the possible Smad complexes are formed in cellular contexts and how these contribute to gene expression. By combining quantitative mass spectrometry with a computational selection strategy, we predict and provide experimental evidence for the three most relevant Smad complexes in the mouse hepatoma cell line Hepa1-6. Utilizing dynamic pathway modeling, we specify the contribution of each Smad complex to the expression of representative Smad target genes, and show that these contributions are conserved in human hepatoma cell lines and primary hepatocytes. We predict, based on gene expression data of patient samples, increased amounts of Smad2/3/4 proteins and Smad2 phosphorylation as hallmarks of hepatocellular carcinoma and experimentally verify this prediction. Our findings demonstrate that modeling approaches can disentangle the complexity of transcription factor complex formation and its impact on gene expression. [less ▲]

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See detailThe Qatar Embargo at the WTO: Finally a Case on Article XXI?
Fahner, Johannes Hendrik UL

Presentation (2017, December 13)

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