References of "1996"
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See detailWie können Trainer und Übungsleiter Kinder und Jugendliche zum Sporttreiben aktivieren?
Steffgen, Georges UL

Scientific Conference (1996, November)

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See detailVoluntary saccadic eye movements: Effect of task repetition. A pet study
Dejardin, S; Dubois, S; Bodart, J.-M et al

Poster (1996, November)

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See detailSportliche Aktivität und Gesundheit - Forschungslage in Luxemburg
Steffgen, Georges UL

Scientific Conference (1996, November)

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See detailInteraction between criteria through the use of fuzzy measures
Marichal, Jean-Luc UL

Presentation (1996, October 24)

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See detailCharacterization of some aggregation functions stable for positive linear transformations
Marichal, Jean-Luc UL; Mathonet, Pierre UL; Tousset, Eric

in Proc. 44th Meeting of the Eur. Working Group "Multiple Criteria Decision Aiding" (MCDA 44), Brussels, Belgium, Oct. 3-4, 1996 (1996, October)

This paper deals with the characterization of some classes of aggregation functions often used in multicriteria decision making problems. The common properties involved in these characterizations are ... [more ▼]

This paper deals with the characterization of some classes of aggregation functions often used in multicriteria decision making problems. The common properties involved in these characterizations are “increasing monotonicity” and “stability for positive linear transformations”. Additional algebraic properties related to associativity allow to completely specify the functions. [less ▲]

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See detailDer Einfluss der Erwartung auf das interpersonelle Verhalten
Krolak-Schwerdt, Sabine UL

Scientific Conference (1996, September)

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See detail« Wir müssen lernen, mit Aggressionen umzugehen »
Weber, Jean-Marie UL

Article for general public (1996)

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See detailDie pschohygienische Funktion des Wert- und Religionsunterrichtes
Weber, Jean-Marie UL

Article for general public (1996)

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See detailEin Verfahren zur Klassifikation zweimodaler binärer Daten
Krolak-Schwerdt, Sabine UL; Orlik, Peter

Scientific Conference (1996, March)

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See detailOn nonstrict means
Fodor, János; Marichal, Jean-Luc UL

Scientific Conference (1996, January)

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See detailPax genes and sclerotome induction
Balling, Rudi UL; Neubüser, A; Christ, B

in Seminars in Cell & Developmental Biology (1996), (7), 129-136

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See detailA role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.
Akasaka, T.; Kanno, M.; Balling, Rudi UL et al

in Development (Cambridge, England) (1996), 122(5), 1513-22

Segment identity in both invertebrates and vertebrates is conferred by spatially restricted distribution of homeotic gene products. In Drosophila, the expression of Homeobox genes during embryogenesis is ... [more ▼]

Segment identity in both invertebrates and vertebrates is conferred by spatially restricted distribution of homeotic gene products. In Drosophila, the expression of Homeobox genes during embryogenesis is initially induced by segmentation gene products and then maintained by Polycomb group and Trithorax group gene products. Polycomb group gene homologs are conserved in vertebrates. Murine mel-18 and closely related bmi-1 are homologous to posterior sex combs and suppressor two of zeste. Mel-18 protein mediates a transcriptional repression via direct binding to specific DNA sequences. To gain further insight into the function of Mel-18, we have inactivated the mel-18 locus by homologous recombination. Mice lacking mel-18 survive to birth and die around 4 weeks after birth after exhibiting strong growth retardation. Similar to the Drosophila posterior sex combs mutant, posterior transformations of the axial skeleton were reproducibly observed in mel-18 mutants. The homeotic transformations were correlated with ectopic expression of Homeobox cluster genes along the anteroposterior axis in the developing paraxial mesoderm. Surprisingly, mel-18-deficient phenotypes are reminiscent of bmi-1 mutants. These results indicate that the vertebrate Polycomb group genes mel-18 and bmi-1, like Drosophila Polycomb group gene products, might play a crucial role in maintaining the silent state of Homeobox gene expression during paraxial mesoderm development. [less ▲]

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See detailPax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
Wallin, J.; Eibel, H.; Neubuser, A. et al

in Development (Cambridge, England) (1996), 122(1), 23-30

Pax1 is a transcriptional regulatory protein expressed during mouse embryogenesis and has been shown to have an important function in vertebral column development. Expression of Pax1 mRNA in the embryonic ... [more ▼]

Pax1 is a transcriptional regulatory protein expressed during mouse embryogenesis and has been shown to have an important function in vertebral column development. Expression of Pax1 mRNA in the embryonic thymus has been reported previously. Here we show that Pax1 protein expression in thymic epithelial cells can be detected throughout thymic development and in the adult. Expression starts in the early endodermal epithelium lining the foregut region and includes the epithelium of the third pharyngeal pouch, a structure giving rise to part of the thymus epithelium. In early stages of thymus development a large proportion of thymus cells expresses Pax1. With increasing age, the proportion of Pax1-expressing cells is reduced and in the adult mouse only a small fraction of cortical thymic stromal cells retains strong Pax1 expression. Expression of Pax1 in thymus epithelium is necessary for establishing the thymus microenvironment required for normal T cell maturation. Mutations in the Pax-1 gene in undulated mice affect not only the total size of the thymus but also the maturation of thymocytes. The number of thymocytes is reduced about 2- to 5-fold, affecting mainly the CD4+8+ immature and CD4+ mature thymocyte subsets. The expression levels of major thymocyte surface markers remains unchanged with the exception of Thy-1 which was found to be expressed at 3- to 4-fold higher levels. [less ▲]

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See detailCytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
Kischkel, F. C.; Hellbardt, S.; Behrmann, Iris UL et al

in EMBO Journal (1996), 14(22), 5579-88

APO-1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to ... [more ▼]

APO-1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces apoptosis upon receptor oligomerization. In a search to identify intracellular signaling molecules coupling to oligomerized APO-1, several cytotoxicity-dependent APO-1-associated proteins (CAP) were immunoprecipitated from the apoptosis-sensitive human leukemic T cell line HUT78 and the lymphoblastoid B cell line SKW6.4. CAP1-3 (27-29 kDa) and CAP4 (55 kDa), instantly detectable after the crosslinking of APO-1, were associated only with aggregated (the signaling form of APO-1) and not with monomeric APO-1. CAP1 and CAP2 were identified as serine phosphorylated MORT1/FADD. The association of CAP1-4 with APO-1 was not observed with C-terminally truncated non-signaling APO-1. In addition, CAP1 and CAP2 did not associate with an APO-1 cytoplasmic tail carrying the lprcg amino acid replacement. Moreover, no APO-1-CAP association was found in the APO-1+, anti-APO-1-resistant pre-B cell line Boe. Our data suggest that in vivo CAP1-4 are the APO-1 apoptosis-transducing molecules. [less ▲]

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