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See detailDepression Burden in Luxembourg: Individual Risk Factors, Geographic Variations and the Role of Migration, 2013-2015 European Health Examination Survey
Ruiz-Castell, Maria; Kandala, Ngianga-Bakwin; Perquin, Magali et al

in Journal of Affective Disorders (2017), 222

Background: Depression is a complex mental disorder that affects an increasing proportion of the worldwide population. This study aims to estimate the prevalence of depressive symptoms in Luxembourg ... [more ▼]

Background: Depression is a complex mental disorder that affects an increasing proportion of the worldwide population. This study aims to estimate the prevalence of depressive symptoms in Luxembourg, associated risk factors and geographic variations. Additionally, it aims to assess whether first and second generation immigrants are at higher risk for depressive symptoms compared to non-immigrants. Methods: Representative cross-sectional data from 1499 residents of Luxembourg, aged 25 to 64 years, were collected from the Luxembourg European Health Survey (EHES-LUX). Depressive symptoms were defined as a score of ≥5 on the Patient Health Questionnaire for depression (PHQ-9) (i.e. mild, moderate or severe). Standard and Bayesian regression models were used to examine associations between depressive symptoms, immigration status and geographic distribution across Luxembourg. Results: The prevalence of depressive symptoms was 21.55% (15.54% mild, 3.54% moderate, and 2.49% moderately severe to severe). The odds of having depressive symptoms was higher among second generation immigrants compared to non-immigrants (OR: 1.58, 95% CI: 1.04, 2.41), independent of socioeconomic and behavioral characteristics. Healthier diet, higher social support and good health perception were protective towards experiencing depressive symptoms. One of the highest likelihoods of reporting depressive symptoms was observed in the South-West of the country with a positive effect at 80% credible region [CR] (1.42 [0.92, 2.73]). Limitations: The participation rate was low (26.7%). The cross-sectional nature of the study does not allow us to establish causality. Conclusions: Depression constitutes an important public health challenge in Luxembourg due to the impact on the overall health of the population. Social programs of health promotion should be developed to improve mental wellbeing in immigrants, especially those of second generation. [less ▲]

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See detailDigital health in ambulatory assessment
Vögele, Claus UL

Book published by INSIDE (2017)

In this volume all accepted contributions to the 5th Biennial Conference of the Society for Ambulatory Assessment are published. The number and quality of these contributions testify to the high standard ... [more ▼]

In this volume all accepted contributions to the 5th Biennial Conference of the Society for Ambulatory Assessment are published. The number and quality of these contributions testify to the high standard of international research in ambulatory monitoring, the rapid advances in technology and data handling supporting ambulatory assessment, and the importance of these developments for the rapidly expanding area of Digital Health. Converging technologies such as Internet applications, social networks, smartphones and wearable sensors in the area of health, are now beginning to transform our approach to health research, healthcare, and communication and access to information. [less ▲]

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See detailMood, emotions and eating disorders
Vögele, Claus UL; Lutz, Annika UL; Gibson, E. Leigh

in Agras, W. Stewart; Hagler Robinson, Athena (Eds.) The Oxford Handbook of Eating Disorders, Second Edition (2017)

Mood and emotions are intrinsically involved with eating. This chapter discusses basic mechanisms, findings, and models that help our understanding of the interactions between eating and emotions, in both ... [more ▼]

Mood and emotions are intrinsically involved with eating. This chapter discusses basic mechanisms, findings, and models that help our understanding of the interactions between eating and emotions, in both clinical and nonclinical populations. The finding that negative affect predicts EDs transdiagnostically, and that comorbidity with depressive disorders and anxiety disorders is the norm among patients with EDs suggests that EDs may not necessarily be restricted to domains of eating behavior and body image but may also be associated with significant difficulties in affective functioning. This chapter reviews the evidence relating to the notion that EDs are disturbances of mood regulation, in which regulatory strategies specifically related to eating and the body are used to diminish negative affect associated with food, body image, or stress. [less ▲]

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See detailPlace, green exercise and stress: an exploration of lived experience and restorative effects
Olafsdottir, Gunnthora; Cloke, Paul; Vögele, Claus UL

in Health & Place (2017)

This paper reports on inter-disciplinary research designed to investigate the stress-buffering effects of green exercise, and the importance of the context in which exercise takes place. This ... [more ▼]

This paper reports on inter-disciplinary research designed to investigate the stress-buffering effects of green exercise, and the importance of the context in which exercise takes place. This investigation of context effects examines both individual physiological responses (salivary cortisol) and the phenomenological interpretation of lived experiences of the intervention, reported by a subsample of participants in a randomized, controlled trial, in which healthy, physically inactive university students were randomly allocated to three activities: walking on a treadmill in a gym, walking in semi-natural recreational area, and sitting and watching nature-based videos on TV. The study found clear indications of context effects, notably in the connections between positive appraisals of perceived circumstances, enjoyment in the enacted context, and physiological stress-reduction. [less ▲]

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See detailGeneralized hypervigilance in fibromyalgia: normal interoceptive accuracy, but reduced self-regulatory capacity
Rost, Silke UL; van Ryckeghem, Dimitri UL; Schulz, André UL et al

in Journal of Psychosomatic Research (2017), 93(2), 48-54

Objective: The factors underlying the aetiology of fibromyalgia (FM) are largely unknown. According to the generalized hypervigilance hypothesis (GHH), FM patients show excessive attention towards pain ... [more ▼]

Objective: The factors underlying the aetiology of fibromyalgia (FM) are largely unknown. According to the generalized hypervigilance hypothesis (GHH), FM patients show excessive attention towards pain stimuli and other sensory events, thereby increasing pain perception and dysfunctional behaviour. We tested this notion by assessing interoceptive accuracy (IA) in FM patients and matched healthy controls. We also tested the hypothesis that FM is characterized by reduced self-regulatory capacity as indexed by heart rate variability (HRV). Methods: 47 FM patients (Mage = 45.5, 39 females) and 45 healthy controls (Mage = 44.9, 37 females) completed several self-report scales (Body Vigilance Scale, Depression Anxiety Stress Scales, Pain Catastrophizing Scale). To derive HRV, heart rate was monitored under resting conditions; for the assessment of IA participants performed a heartbeat tracking task in which they were asked to silently count their heartbeats. Results: FM patients reported higher body vigilance than healthy controls, but there were no group differences in IA. FM patients had lower HRV compared with healthy controls. HRV did not predictor IA. Conclusion: In conclusion, our findings do not support the hypothesis of generalized hypervigilance in FM patients. Patients reported a heightened focus on bodily sensations, which was not reflected in IA. It may be that hypervigilance is not a general and stable characteristic but is rather context dependent and modality-specific. [less ▲]

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See detailGrand challenges in eating behavior research: preventing weight gain, facilitating long-term weight maintenance
Meule, Adrian; Vögele, Claus UL

in Frontiers in Psychology (2017), 8

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See detailGastric modulation of startle eye blink
Schulz, André UL; Van Dyck; Lutz, Annika UL et al

in Biological Psychology (2017), 127(1), 25-33

Abstract: Previous assessment methods of gastric interoception either rely on self-reports, or imply invasive procedures. We investigated the reliability of startle methodology as a non-invasive ... [more ▼]

Abstract: Previous assessment methods of gastric interoception either rely on self-reports, or imply invasive procedures. We investigated the reliability of startle methodology as a non-invasive alternative for the assessment of afferent gastric signals. Twenty-four participants were tested on three separate days, on which they were requested to ingest water (either 0, 300 or 600 ml), after 8 h of fasting. On each assessment day, eye blink responses (EMG) to 10 acoustic startle stimuli (105 dB) were assessed at 4 measurement points (before, 0, 7, 14 min. after ingestion). Increased normogastric responses (EGG), ratings of satiety and fullness, and higher heart rate variability (RMSSD) suggested effective non-invasive induction of gastric distention. Startle responses were lower directly after ingestion of 600 ml as compared to earlier and later measurements. These results suggest that startle methodology provides a reliable method to investigate afferent gastric signals. It could be useful to study possible dissociations between subjective reports and objective afferent gastric signals in eating or somatoform disorders. [less ▲]

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See detailLangzeitkonsequenzen von frühkindlichem Stress
Schaan, Violetta UL; Schulz, André UL; Vögele, Claus UL

Poster (2017)

Traumatische Belastungen während der Kindheit können das Risiko für die Entwicklung unsicherer Bindungsstile erhöhen, die bereits mit langfristigen psychischen und körperlichen Gesundheitsproblemen in ... [more ▼]

Traumatische Belastungen während der Kindheit können das Risiko für die Entwicklung unsicherer Bindungsstile erhöhen, die bereits mit langfristigen psychischen und körperlichen Gesundheitsproblemen in Beziehung gebracht wurden. Die zugrundeliegenden Prozesse sind allerdings noch weitestgehend unklar. Wir präsentieren zwei Studien, die den Zusammenhang zwischen kindlichem Stress und Gesundheit im Erwachsenenalter sowie Körperwahrnehmung und Gedächtnisfähigkeit untersuchen. In der ersten Studie nahmen 199 Teilnehmer an einer Onlineumfrage teil, bei der Gesundheit, frühkindliches Trauma, Resilienz und Zurückweisungssensitivität gemessen wurden. Teilnehmer mit geschiedenen Eltern berichteten erhöhte psychische Belastungswerte, kindliches Trauma, Zurückweisungssensitivität und weniger Resilienz. Die Beziehung zwischen elterlicher Scheidung und psychischer Gesundheit konnte vollständig durch diese vier Faktoren erklärt werden (Varianzaufklärung 44%). In einer zweiten Studie wurden bei 60 Teilnehmern verschiedene Selbstbericht-Parameter erhoben und die Gedächtnis- und Interozeptionsfähigkeit vor und nach einem Stresstest untersucht. Erwachsene mit einer Vorgeschichte von elterlicher Trennung berichteten mehr bindungsbezogene Angst und Vermeidung als Kontrollpersonen. Das Erlebnis einer elterlichen Scheidung war negativ mit der Gedächtnisleistung nach dem Stresstest korreliert. Weiterhin weisen die Ergebnisse auf einen quadratischen Zusammenhang zwischen Stress und Interozeptionsfähigkeit hin. [less ▲]

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See detailSleep and somatic complaints in university students
Schlarb, Angelika; Claßen, Merle; Hellmann, Sara et al

in Journal of Pain Research (2017), 10

Background: Sleep problems are common among university students. Poor sleep is associated with impaired daily functioning, increased risk of psychiatric symptoms, and somatic complaints such as pain ... [more ▼]

Background: Sleep problems are common among university students. Poor sleep is associated with impaired daily functioning, increased risk of psychiatric symptoms, and somatic complaints such as pain. Previous results suggest that poor sleep exacerbates pain, which in turn negatively affects sleep. The purpose of the present study was to determine prevalence rates, comorbidity, and role of depression as a factor of moderating the relationship between sleep and physical complaints in German university students. Samples and methods: In total, 2443 German university students (65% women) completed a web survey. Self-report measures included the Pittsburg Sleep Quality Index, three modules of the Patient Health Questionnaire, and a questionnaire on the functional somatic syndromes (FSSs). Results: More than one-third (36.9%) reported poor sleep as assessed by the Pittsburgh Sleep Quality Index. Somatoform syndrome was identified in 23.5%, and the prevalence of any FSS was 12.8%. Self-reported sleep quality, sleep onset latency, sleep disturbances, use of sleep medications, and daytime dysfunctioning were significant predictors of somatoform syndrome, whereas sleep efficiency and sleep duration influenced somatic complaints indirectly. Moderate correlations were found between stress, anxiety, somatoform syndrome, depression, and overall sleep quality. The effect of somatic complaints on sleep quality was associated with the severity of depression. Anxiety shows direct effects on somatization and depression but only indirect associations with sleep quality. [less ▲]

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See detailLangzeitkonsequenzen von frühkindlichem Stress: quadratischer Zusammenhang zwischen Stress und Interozeptionsfähigkeit
Schaan, Violetta UL; Schulz, André UL; Vögele, Claus UL

in Schächinger, H. (Ed.) Abstractband 43. Tagung Psychologie und Gehirn (2017)

Traumatische Belastungen während der Kindheit können das Risiko für die Entwicklung unsicherer Bindungsstile erhöhen, die bereits mit langfristigen psychischen und körperlichen Gesundheitsproblemen in ... [more ▼]

Traumatische Belastungen während der Kindheit können das Risiko für die Entwicklung unsicherer Bindungsstile erhöhen, die bereits mit langfristigen psychischen und körperlichen Gesundheitsproblemen in Beziehung gebracht wurden. Die zugrundeliegenden Prozesse sind allerdings noch weitestgehend unklar. Da interozeptive Signale die Regulation negativer Emotionen als Reaktion auf sozialer Zurückweisung begünstigen können, die infolge einer Stressbelastung verändert sein könnten, wurde insbesondere der Effekt von kindlichem Stress auf Interozeption untersucht. Wir präsentieren zwei Studien, die den Zusammenhang zwischen kindlichem Stress und Gesundheit im Erwachsenenalter sowie Körperwahrnehmung und Gedächtnisfähigkeit untersuchen. In der ersten Studie nahmen 199 Teilnehmer an einer Onlineumfrage teil, bei der Gesundheit, frühkindliches Trauma, Resilienz und Zurückweisungssensitivität gemessen wurden. Teilnehmer mit geschiedenen Eltern berichteten erhöhte psychische Belastungswerte, kindliches Trauma, Zurückweisungssensitivität und weniger Resilienz. Die Beziehung zwischen elterlicher Scheidung und psychischer Gesundheit konnte vollständig durch diese vier Faktoren erklärt werden (Varianzaufklärung 44%). In einer zweiten Studie wurden bei 60 Teilnehmern verschiedene Selbstberichts-Parameter erhoben und die Gedächtnis- und Interozeptionsfähigkeit (Schandry Herzschlagwahrnehmungstest/EKG) vor und nach einem sozial-evaluativen Kaltwasser-Stresstest untersucht. Die Reaktion des autonomen Nervensystems wurde mithilfe von Herzraten- und Blutdruckvariabilität bestimmt. Erwachsene mit einer Vorgeschichte von elterlicher Trennung berichteten mehr bindungsbezogene Angst und Vermeidung als Kontrollpersonen. Das Erlebnis einer elterlichen Scheidung war negativ mit der Gedächtnisleistung nach dem Stresstest korreliert. Weiterhin weisen die Ergebnisse auf einen quadratischen Zusammenhang zwischen kindlicher Stressbelastung und Interozeptionsfähigkeit hin. Basierend auf diesen Ergebnissen könnte ein ‚gesunder Normbereich‘ der Interozeptionsfähigkeit existieren. Kindlicher Stress könnte sowohl eine Verringerung, als auch eine Erhöhung der Interozeptionsfähigkeit bewirken, was beides mit gesundheitlichen Problemen assoziiert sein könnte. [less ▲]

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See detailSleep disturbances and mental strain in university students: results from an online survey in Luxembourg and Germany
Schlarb, Angelika; Claßen, Merle; Grünewald, Julia et al

in International Journal of Mental Health Systems (2017), 11

OBJECTIVES: This study examined the prevalence of sleep disturbances and mental strain in students from two European countries, Luxembourg and Germany. METHODS: A total of 2831 students took part in an ... [more ▼]

OBJECTIVES: This study examined the prevalence of sleep disturbances and mental strain in students from two European countries, Luxembourg and Germany. METHODS: A total of 2831 students took part in an online survey, with 2777 students from Germany and 184 students from Luxembourg. Sleep disturbances were assessed with the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale, and aspects of mental strain using the Patient Health Questionnaire, the Social-Interactive-Anxiety Scale, the self-efficacy questionnaire and the test anxiety questionnaire. In addition, we also assessed students' chronotypes. RESULTS: Across the whole sample mean scores on the sleep questionnaires were above the cut-off for clinically relevant sleep problems, indicating an increased prevalence of sleep disturbances in students from both countries. Sleep quality was impaired in 42.8%, and 17.9% showed clinically relevant scores. Overall 25.5% reported elevated depression and 13.3% social phobia symptoms, while 45% indicated elevated stress levels. Sleep quality, daytime sleepiness, chronotype, depression scores, stress levels, test anxiety, and self-efficacy differed significantly between men and women, but there were no differences between countries. CONCLUSIONS: Sleep disturbances and mental strain in students are common, with the current results replicating previous findings. Students from Luxembourg and Germany are affected equally. [less ▲]

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See detailAngst vor körperlicher Bewegung bei Patienten mit Herzinsuffizienz und gesunden Senioren – Ein psychophysiologisches Experiment basierend auf dem Schreckreflex-Paradigma
Hoffmann, Jeremy; Finke, Johannes; Vögele, Claus UL et al

in Schorr, A. (Ed.) Abstractband 13. Kongress der Fachgruppe Gesundheitspsychologie der DGPs (2017)

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See detailZusammenhang zwischen interozeptiver Genauigkeit und kardiovaskulärer Veränderung nach akutem Stress bei gesunden Frauen
Rost, Silke UL; Van Dyck, Zoé UL; Schulz, André UL et al

in Schächinger, H. (Ed.) Abstractband 43. Tagung Psychologie und Gehirn (2017)

Einleitung:Interozeption als afferente und Stressverarbeitung als efferente Informationsverarbeitung können als komplementär hinsichtlich der Kommunikation zwischen Körper und Gehirn verstanden werden. Es ... [more ▼]

Einleitung:Interozeption als afferente und Stressverarbeitung als efferente Informationsverarbeitung können als komplementär hinsichtlich der Kommunikation zwischen Körper und Gehirn verstanden werden. Es wurde gezeigt, dass stressbedingte veränderte kardiovaskuläre Prozesse mit veränderter Interozeption zusammenhängen und in körperlichen Beschwerden resultieren können. Wenig erforscht ist in diesem Kontext jedoch die psychologische sowie physiologische Erregung, welche mit einem akuten mentalen Stressor einhergeht. Ziel der vorliegenden Studie ist es, diese Lücke zu schließen und den Zusammenhang zwischen interozeptiver Genauigkeit und kardiovaskulärer Reaktivität und Erholung nach einem mentalen Stressor in einer gesunden Stichprobe zu untersuchen. Methode: Es wurde die Pulsfrequenz von 69 Frauen (MAlter = 24.20 Jahre, Range 18-50 Jahre; MBMI = 23.19, Range 17.19-34.48) zur späteren Bestimmung der Herzratenvariabilität (HRV) gemessen. Zur Bestimmung der interozeptiven Genauigkeiten führten die Teilnehmerinnen eine Herzschlagzählaufgabe durch und als mentalen Stressor setzten wir eine choice reaction time task (CRTT) ein. Die Pulsfrequenz wurde während der CRTT sowie während einer 10-minütigen Erholungsphase aufgezeichnet um Werte der kardiovaskulären Stressreaktivität und – erholung zu erfassen. Ergebnisse: DieErgebnisse zeigten keinen Zusammenhang zwischen interozeptiver Genauigkeit und HRV-Reaktivität auf akuten mentalen Stress (r = .042, p = .785). Der Zusammenhang zwischen interozeptiver Genauigkeit und kardiovaskulärer Stresserholung nach der CRTT war negativ (r = -.377; p = .012). Diskussion: Ergebnisse der vorliegenden Studie liefern erste Hinweise dafür, dass eine gute Interozeptionsfähigkeit mit einer besseren kardiovaskulären Erholung nach einem mentalen Stressor zusammenhängen, d.h. kardiovaskuläre Prozesse positiv beeinflussen kann. Interventionen zur Verbesserung der Interozeptionsfähigkeit könnten kardiovaskuläre Erholung erleichtern und das damit einhergehende Risiko zukünftiger Herz-Kreislauf- Probleme verringern. [less ▲]

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See detailGreen exercise is associated with better cell ageing profiles
Olafsdottir, Gunnthora; Cloke, Paul; Epel, Elissa et al

in The European Journal of Public Health (2016, November 01), 26(Suppl 1), 165021

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See detailResilience and rejection sensitivity mediate long-term outcomes of parental divorce
Schaan, Violetta UL; Vögele, Claus UL

in European Child & Adolescent Psychiatry (2016), 25(11), 1267-1269

Introduction: Increasing divorce rates leave more and more children to deal with the separation of their parents. Recent research suggests that children of divorced parents more often experience ... [more ▼]

Introduction: Increasing divorce rates leave more and more children to deal with the separation of their parents. Recent research suggests that children of divorced parents more often experience psychological and physical symptoms than children of non-divorced parents. The processes that mediate the relationship between parental divorce and ill-health, however, are still elusive. The current study investigated the mediating role of psychological factors such as resilience and rejection sensitivity on the long-term consequences of parental divorce in young adults. Methods: One hundred and ninety-nine participants (mean age 22.3 years) completed an online survey including measures of mental health, childhood trauma, resilience and rejection sensitivity. Results: Participants with divorced parents (33%) reported increased levels of psychological symptoms, childhood trauma, rejection sensitivity and lower levels of resilience. The association between parental divorce and mental health was fully mediated by resilience, rejection sensitivity and childhood trauma. The mediation model explained up to 44% of the total variance in mental health symptoms. Discussion: Resilience and rejection sensitivity are crucial factors for successful coping with the experience of parental separation. Prevention programs that help to boost children’s resilience might help to reduce the long-term effects of parental divorce on their attachment style (e.g. rejection sensitivity), thereby improving their mental health on the long run. Furthermore, the results call for parental awareness and counseling to target and reduce the observed increased level of childhood trauma. Limitations concern the cross-sectional and retrospective design of the study. [less ▲]

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See detailThe Water Load Test As a Measure of Gastric Interoception: Development of a Two-Stage Protocol and Application to a Healthy Female Population
Van Dyck, Zoé UL; Vögele, Claus UL; Blechert, Jens et al

in PLoS ONE (2016), 11(9), 0163574

The sensitivity for one’s own internal body signals (i.e., interoception) has been demonstrated to play an important role in the pathogenesis of eating and weight disorders. Most previous measures ... [more ▼]

The sensitivity for one’s own internal body signals (i.e., interoception) has been demonstrated to play an important role in the pathogenesis of eating and weight disorders. Most previous measures assessing interoceptive processing have not, or only partly, captured perception of hunger and satiety cues, which is a core aspect of interoceptive deficits in eating disorders. In addition, methods used to measure sensitivity to gastric signals are heterogeneous and findings inconsistent. The primary aim of the present study was to establish a standardised test to measure gastric interoception, and to provide normative data using a non-clinical adult sample. The two-step Water Load Test (WLT-II) involves ingestion of non-caloric water until perceived satiation (step 1) and until maximum fullness (step 2). The WLT-II consists of several variables: Besides volumes of water ingested until satiation and maximum fullness expressed in ml, percentage of satiation to maximum fullness is calculated as an individual index of gastric interoception that is not confounded with stomach capacity. Ninety-nine healthy women participated in the study. Measures included the WLT-II, the heartbeat tracking test, a self-report questionnaire assessing subjective sensations, and the Eating Disorder Inventory-2. Twenty-eight participants underwent test-retest of the WLT-II. Results suggest that the WLT-II is a valid and reliable measure of gastric interoception. Importantly, satiation volume and percentage of satiation to maximum fullness were strongly positively related to self-reported bulimic symptoms, indicating that the WLT-II could emerge as a useful clinical tool to measure interoceptive processing in the field of eating disorders. [less ▲]

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See detailCardiac modulation of startle is altered in depersonalization-/derealization disorder: evidence for impaired brainstem representation of baro-afferent neural traffic
Schulz, André UL; Matthey, J. H.; Vögele, Claus UL et al

in Psychiatry Research (2016), 240(1), 4-10

Patients with depersonalization-/derealization disorder (DPD) show altered heartbeat-evoked brain potentials, which are considered psychophysiological indicators of cortical representation of visceral ... [more ▼]

Patients with depersonalization-/derealization disorder (DPD) show altered heartbeat-evoked brain potentials, which are considered psychophysiological indicators of cortical representation of visceral-afferent neural signals. The aim of the current investigation was to clarify whether the impaired CNS representation of visceral-afferent neural signals in DPD is restricted to the cortical level or is also present in sub-cortical structures. We used cardiac modulation of startle (CMS) to assess baro-afferent signal transmission at brainstem level in 22 DPD and 23 healthy control individuals. The CMS paradigm involved acoustic startle stimuli (105 dB(A), 50 ms) elicited 0, 100, 200, 300, 400 and 500 ms after a cardiac R-wave. In healthy control individuals, we observed lower startle responses at 100 and 300 ms than at 0 and 400 ms after an R-wave. In DPD patients, no effect of the cardiac cycle on startle response magnitude was found. We conclude that the representation of visceral-afferent neural signals at brainstem level may be deficient in DPD. This effect may be due to increased peripheral sympathetic tone or to dysregulated signal processing at brainstem level. [less ▲]

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See detailEarly life adversity associates with increased depressive symptoms and few active T cells in adulthood
Elwenspoek, Martha; Schaan, Violetta UL; Hengesch, Xenia et al

Poster (2016, June)

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See detailA meta-analysis on resting state high-frequency heart rate variability in Bulimia Nervosa
Peschel, Stephanie K.V.; Feeling, Nicole R.; Vögele, Claus UL et al

in European Eating Disorders Review (2016), 24(5), 355-365

Objective: Autonomic nervous system (ANS) function is altered in eating disorders. We aimed to quantify differences in resting state vagal activity, indexed by high-frequency heart rate variability (HF ... [more ▼]

Objective: Autonomic nervous system (ANS) function is altered in eating disorders. We aimed to quantify differences in resting state vagal activity, indexed by high-frequency heart rate variability (HF-HRV) comparing patients with bulimia nervosa (BN) and healthy controls. Methods: A systematic search of the literature to identify studies eligible for inclusion and meta-analytical methods were applied. Meta-regression was used to identify potential covariates. Results: 8 studies reporting measures of resting HF-HRV in individuals with BN (n=137) and controls (n=190) were included. Random-effects meta-analysis revealed a sizeable main effect (Z=2.22, p=.03; Hedge’s g=0.52, 95%CI[0.06;0.98]) indicating higher resting state vagal activity in individuals with BN. Meta-regression showed that BMI and medication intake are significant covariates. Discussion: Findings suggest higher vagal activity in BN at rest, particularly in un-medicated samples with lower body mass index. Potential mechanisms underlying these findings and implications for routine clinical care are discussed. [less ▲]

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