References of "Levy-Marchal, C"
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See detailGeographical variation of presentation at diagnosis of type 1 diabetes in children: the EURODIAB Study
Levy-Marchal, C.; Patterson, C.C.; Green, A. et al

in Diabetologia (2001), 44(3), 75-80

We aimed to describe the frequency and degree of diabetic ketoacidosis in children across Europe at the time of diagnosis of Type I (insulin-dependent) diabetes mellitus and to determine if factors such ... [more ▼]

We aimed to describe the frequency and degree of diabetic ketoacidosis in children across Europe at the time of diagnosis of Type I (insulin-dependent) diabetes mellitus and to determine if factors such as age and geographical region contribute to the risk of diabetic ketoacidosis. METHODS: The study was part of the EURODIAB project. A total of 24 centres, covering a population at risk of more than 15 million children below 15 years of age, recruited 1,260 children at the time of clinical diagnosis. RESULTS: Polyuria, by far the most frequent symptom, was observed in 96% of the children. In only 25% of the children was the duration of symptoms less than 2 weeks and this proportion was larger in the under 5 year age-group (37 vs 22%; p < 0. 001). Of the 11 centres that recorded diabetic ketoacidosis status, the overall proportion with diabetic ketoacidosis (pH < 7.3) was 40% (95%-CI: 36-44%) in at least 90 % of cases. After stratification by centre, the odds ratio for diabetic ketoacidosis in the under 5 age-group was 1.02 (95%-CI:0.69-1.49) relative to the older children. There was significant variation between the 11 centres in the frequency of diabetic ketoacidosis which ranged from 26 to 67% (p = 0.002). An inverse correlation between the frequency of diabetic ketoacidosis and the background incidence rate was found in these centres (Spearman's rank correlation, rs = -0.715;p = 0.012). CONCLUSION/INTERPRETATION: Rising standards of medical information and greater awareness concurrent with an overall increase in incidence could have resulted in changes in the clinical presentation at onset of Type I childhood diabetes in Europe. [less ▲]

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See detailClinical and laboratory features of type 1 diabetic children at the time of diagnosis
Levy-Marchal, C.; Papoz, L.; De Beaufort, Carine UL et al

in Diabetic Medicine : A Journal of the British Diabetic Association (1992), 9

Detailed reference viewed: 37 (0 UL)
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See detailIncidence du diabète insulino-dépendant, survenant avant l’âge de 20 ans en France
Levy-Marchal, C.; Pappoz, L.; De Beaufort, Carine UL et al

in Pediatrie (1991), 46

Detailed reference viewed: 16 (0 UL)
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See detailIncidence of juvenile type 1 (insulin dependent) diabetes mellitus in France
Levy-Marchal, C.; Papoz, L.; De Beaufort, Carine UL et al

in Diabetologia (1990), 33

Detailed reference viewed: 42 (0 UL)
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See detailThe Fourth International Workshop on the Standardisation of Insulin Autoantibody Measurement
Kolb, H.; Arnaiz-Villena, A.; De Beaufort, Carine UL et al

in Diabetologia (1990), 33(10), 638-639

[No abstract available]

Detailed reference viewed: 43 (0 UL)